Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Experimental Design for the toxicity Studies in Dogs
| Group | Treatment | Dose Level (mg/kg/day) |
No. Doses |
Total Dose (mg/kg) |
Main groups animal |
Recovery Group animals |
|---|---|---|---|---|---|---|
|
| ||||||
| 1 | Vehicle | 0 | 7 | 0 | 3M/3F | 2M/2F |
| 2 | 100x human dose | 0.4 | 7 | 2.8 | 3M/3F | 2M/2F |
| 3 | 100x human dose | 0.4 | 1 | 0.4 | 3M/3F | 2M/2F |
| 4 | 1000x human dose | 4 | 1 | 4 | 3M/3F | 2M/2F |
