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[Preprint]. 2023 May 18:rs.3.rs-2800118. [Version 1] doi: 10.21203/rs.3.rs-2800118/v1

Table 1. Summary of sequences and structures of anti-SARS-CoV-2 antibodies and nanobodies.

The sequences and origin/source are collected in CovAbDab 23, as of 12/20/2022. The number of structures of antibodies and nanobodies in complex with RBD or spike protein are downloaded from PDB.

Origin/Source Sequences Structures *
(PDB ID)
Total Antibodies 6746 340
  Human (patient or vaccinee) 6321 250
  Mouse (immunized/humanized) 165 40
  Phage Display Library or engineered 225 33
  Undefined 35 25
Total Nanobodies 620 83
  Immunized (Alpaca/Camel/llama#) 332 (123/18/189) 50 (16/5/27)
  Phage display library 276 23
  Undefined 14 12
*

Unique non-redundant structures determined either by X-ray or cryo-EM as listed in the PDB.

#

This includes two sequences/structures from mice engineered to express llama Nb genes 64.