Table 2.

Duration of antibiotic treatment

Situation	Treatment time
Afebrile, no defined focus, with response to initial antimicrobial regimen	48 hours afebrile if neutrophils above 500 cells/mm³
Afebrile, without a defined focus, with response to modified treatment	7 days afebrile if neutrophils less than 500 cells/mm³
Afebrile and with a defined focus	Suggested time for the site in question
Infection of skin and soft tissues	Duration of treatment: 7-14 days
Bloodstream infection	Gram-negative: 10-14 days
	Coagulase-negative Staphylococcus: 7 days
	Staphylococcus aureus: 14 days + transesophageal echo
	Candida sp.: 14 days after negative blood culture + transesophageal echo
Catheter-related infection	Remove catheter if infection by Staphylococcus aureus, Candida Sp or tunnel infection
Bacterial pneumonia	Duration of treatment: 7 days
Diarrhea due to Clostridioides difficile	Duration of treatment: 10-14 days