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Serum-free medium, confocal images of TJ protein ZO-1 (red), Claudin 5 (green) expression on astrocytes and pericytes (a) or following treatment with Zn sulfate (b) and for hBMECs (c) following treatment with Zn (d) localized to transwell insert membrane in BBB model. The nucleus was stained with DAPI.
Abbreviations- Zn, zinc; TJ, tight junctions; Z0-1, Zona occludens; hBMEC, Human brain microvascular endothelial cells; DAPI, 4',6-diamidino-2-phenylindole; BBB, blood brain barrier.
