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Dose–response curves of kinase inhibitors tested against PLpro. (A) Olmutinib, IC50 0.54 ± 0.04 μM, (B) Dacomitinib, IC50 3.30 ± 0.06 μM, (C) Crizotinib 3.80 ± 0.04 μM, and (D) Bosutinib IC50 4.20 ± 0.28 μM. All experiments were performed in triplicate, and all data are expressed as the mean ± standard deviation.
