Table 1. Compounds Identified against Plpro and Mpro from the Microsource Spectrum Collection Library Screena.
compound | PLpro IC50 (μM) | Mpro IC50 (μM) |
---|---|---|
raloxifene | 3.28 ± 0.29 | 42.8 ± 6.7 |
cetylpyridinium chloride | 2.72 ± 0.09 | 7.25 ± 0.15 |
cefonicid sodium | 2.17 ± 1.2 | |
citicoline | 1.35 ± 0.27 | |
colistin sulfate | 2.94 ± 0.54 | |
β-lapachone | 5.30 ± 0.29 | |
tanshinone iia sulfonate sodium | 2.76 ± 0.28 | |
lobaric acid | 10 ± 1.11 |
It should be noted that compounds such as β-lapachone and tanshinone may be potential false positives involved in redox cycling.18