Table 2.
Significant interactions between inflammatory markers and race on nodal strength in a priori regions of interest in the full sample.
Region of Interest | β (SE) | t-value | p-value | partial η2 |
---|---|---|---|---|
| ||||
CRP | ||||
| ||||
Putamen | ||||
FSRP-10 | −.208 (.112) | −1.859 | .068 | .050 |
BMI | −.014 (.006) | −2.522 | .014 | .089 |
pVIQ | −.003 (.004) | −.842 | .403 | .011 |
WMH | .243 (.077) | 3.138 | .003 | .132 |
ICV | −2.12E−7 (1.87E−7) | −1.130 | .262 | .019 |
Race | .275 (.149) | 1.845 | .070 | .050 |
CRP | .021 (.027) | .772 | .443 | .009 |
CRP*Race Interaction | −.080 (.037) | −2.149 | .035 | .066 |
| ||||
IL-1β (n=65) | ||||
| ||||
Pars Opercularis | ||||
FSRP-10 | −.015 (.015) | −.978 | .332 | .017 |
BMI | .0002 (.001) | .239 | .812 | .001 |
pVIQ | −.001 (.001) | −2.447 | .018 | .097 |
WMH | .009 (.011) | .833 | .408 | .012 |
ICV | −3.00E−8 (2.65E−8) | −1.132 | .263 | .022 |
Race | .164 (.101 | 1.622 | .111 | .045 |
IL-1β | .239 (.114) | 2.094 | .041 | .073 |
IL-1β*Race Interaction | −.365 (.180) | −2.025 | .048 | .068 |
| ||||
IL-6 | NS | NS | NS | NS |
Note: Entries reflect full linear regression model interaction results for the interaction of inflammatory markers and race on nodal strength. FSRP-10 and WMH were log-transformed and IL-1β was winsorized for data normalization. pVIQ = predicted verbal intelligence quotient derived from the Wechsler Test of Adult Reading; HAM-D=Hamilton Depression Rating Scale score; FSRP-10=Framingham Stroke Risk Profile 10-year percent risk of stroke; BMI=body mass index; WMH=white matter hyperintensity; ICV=intracranial volume; IL-6 = Interleukin-6; CRP = C-Reactive Protein; IL-1β = Interleukin 1-beta; NS = not significant.