Table 1.
Relationship between expression of syncytin-1 and preeclampsia
| Type of cancer | Specimen | Stage(w)/Number of cases | Area | Methods | Upstream factors | Expression | Ref. |
|---|---|---|---|---|---|---|---|
| Preeclampsia | Tissue |
9-21w/11 late/(N:17,P:21) |
USA Belgium |
in-situ hybridization IHC |
unk | Low | [77] |
| Cell | unk/unk | Germany |
RT-PCR sqPCR ELISA WB |
PPARγ/RXRα | Low | [79] | |
| Tissue |
N/(n = 8) MPE/(n = 9) SPE/(n = 7) |
Canada |
cell fusion assay RT-PCR WB |
unk | Low | [78] | |
| Tissue | 31-41w/(N:12,P:8) | USA | RT-PCR |
DNMT1 DNMT3B3 Hypermethylation |
Low | [76] | |
| Tissue |
First trimester/unk second trimester/unk term/unk |
UK |
qRT-PCR WB |
unk | Slightly high | [80] |
unk unknown; P preeclampsia; N normal; CT cytotrophoblast; WB Western Blot; MPE moderated preeclampsia; SPE severe preeclampsia