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. 2023 Jun 16;14:104. doi: 10.1007/s12672-023-00702-6

Table 1.

Relationship between expression of syncytin-1 and preeclampsia

Type of cancer Specimen Stage(w)/Number of cases Area Methods Upstream factors Expression Ref.
Preeclampsia Tissue

9-21w/11

late/(N:17,P:21)

USA

Belgium

in-situ hybridization

IHC

unk Low [77]
Cell unk/unk Germany

RT-PCR

sqPCR

ELISA

WB

PPARγ/RXRα Low [79]
Tissue

N/(n = 8)

MPE/(n = 9)

SPE/(n = 7)

Canada

cell fusion assay

RT-PCR

WB

unk Low [78]
Tissue 31-41w/(N:12,P:8) USA RT-PCR

DNMT1

DNMT3B3

Hypermethylation

Low [76]
Tissue

First trimester/unk

second trimester/unk

term/unk

UK

qRT-PCR

WB

unk Slightly high [80]

unk unknown; P preeclampsia; N normal; CT cytotrophoblast; WB Western Blot; MPE moderated preeclampsia; SPE severe preeclampsia