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. 2023 Jun 16;14:104. doi: 10.1007/s12672-023-00702-6

Table 2.

Relationship between high expression of syncytin-1 and neuroblastoma

Type of cancer Specimen Cell lines Methods Upstream
factors
Downstream factors Signal pathway Oncogenic effect Ref.
Neuroblastoma Cell SH-SY5Y

Semi-qPCR

qRT-PCR

WB

Caffeine

aspirin

unk unk Proliferation [100]
Cell

SH-SY5Y

SK-N-AS

SK-N-DZ

qRT-PCR

Oxygen tension

DNA methylation

unk unk Proliferation [99]
Cell

SH-SY5Y

IMR-32

SiMa

qRT-PCR

Culture medium

micro-environmnt

unk unk

Proliferation

invasion

[96]
Cell

SH-SY5Y

IMR-32

qPCR

WB

unk Calcium influx

TRPC3

DISC1

Proliferation [97]
Cell

SH-SY5Y

IMR-32

qRT-PCR

WB

unk Calcium influx SK3

Proliferation

migration

[98]

unk  unknown; WB  Western Blot