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. 2023 Jun 16;14:104. doi: 10.1007/s12672-023-00702-6

Table 3.

Relationship between high expression of syncytin-1 and endometrial cancer

Type of cancer Specimen Number of cases Methods Upstream factors Downstream factors Oncogenic effect Relationship between high expression of syncytin-1 and endometrial cancer: Ref.
Clinical parameter Relevance
Endometrial cancer Tissue 48/(E:24,N:24)

qPCR

RT-PCR

Northern Blot

Steroids

CAMP

unk

Fusion

proliferation

unk unk [113]
Tissue 67/(E:38,N:29) qPCR Hypomethylation unk Proliferation

TNM

staging

 +  [114]
Histological grading  + 
Tissue cell 167/(E:130,N:37) RT-PCR unk

Waveform

E-adhesion

Fusion

proliferation

migration

unk unk [115]

unk unknown; E endometrial cancer; N normal; + positive correlation