Table 3.
Type of cancer | Specimen | Number of cases | Methods | Upstream factors | Downstream factors | Oncogenic effect | Relationship between high expression of syncytin-1 and endometrial cancer: | Ref. | |
---|---|---|---|---|---|---|---|---|---|
Clinical parameter | Relevance | ||||||||
Endometrial cancer | Tissue | 48/(E:24,N:24) |
qPCR RT-PCR Northern Blot |
Steroids CAMP |
unk |
Fusion proliferation |
unk | unk | [113] |
Tissue | 67/(E:38,N:29) | qPCR | Hypomethylation | unk | Proliferation |
TNM staging |
+ | [114] | |
Histological grading | + | ||||||||
Tissue cell | 167/(E:130,N:37) | RT-PCR | unk |
Waveform E-adhesion |
Fusion proliferation migration |
unk | unk | [115] |
unk unknown; E endometrial cancer; N normal; + positive correlation