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. 2023 Jun 16;13:9790. doi: 10.1038/s41598-023-36375-y

Table 3.

Multivariate logistic and cox-proportional hazards regressions of predictors associated with raised RVSP at baseline and death at 6 months of follow-up, respectively.

Variables Baseline moderate to severe RVSPa Mortality rate at 6 months
aOR, 95%CI P value HIV-unadjustedb HIV-adjustedc
aHR, 95%CI P value aHR, 95%CI P value
Use of biomass fuel 3.07, 1.02–9.28 0.046
Unknown HIV status 2.73, 0.96–7.73 0.07
NYHA FC III/IV 4.18, 1.01–17.38 0.049 4.2, 0.96–18.47 0.058 5.03, 1.53–16.51 0.008
RVSP (mmHg) 1.07, 1.03–1.11 0.001 1.08, 1.02–1.13 0.004
IVSS 1.25, 1.07–1.46 0.005 1.2, 1.00–1.43 0.051
BMI (kg/m2) 0.75, 0.8–0.98 0.034 0.77, 0.59–1.00 0.05
Alcohol abuse 4.77, 0.60–37.97 0.14 7.14, 1.04–49.07 0.046

RVSP: right ventricular systolic pressure, NYHA/FC: New York Heart Association Functional Classification, BMI: Body Mass Index, IVSS: interventricular septum systolic, TAPSE: tricuspid annular plane systolic excursion.

aModel adjusted for sex, age, occupation type, diabetes, hypertension, exposure to schistosomiasis, alcohol abuse, rheumatic diseases, peripheral oedema, and 6 min walking distance.

bModel adjusted for age, sex, smoking habit, left atrial size, TAPSE, pulse at rest, hypercholesterolemia, alcohol abuse and ejection fraction calculated (EF).