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. 2023 Jun 16;13:9755. doi: 10.1038/s41598-023-36639-7

Table 2.

Logistic regression to predict amyloid-beta positivity in patients with mild cognitive impairment using demographics and magnetic resonance image features.

Logistic regression Support vector model Random forest
Mean SD p Mean SD p Mean SD p
Step 1 Demographic features
 Age, sex, education 0.52 0.08  < 0.001 0.51 0.08  < 0.001 0.55 0.08  < 0.001
 Age, sex, education + MMSE (total) 0.58 0.09  < 0.001 0.56 0.09  < 0.001 0.64 0.08 0.059
 Age, sex, education + SNSB (detailed) 0.69 0.08 Ref 0.69 0.08 Ref 0.66 0.08 Ref
Step 2 T1-weighted magnetic resonance image
 Age, sex, education + SNSB (detailed) 0.69 0.08 Ref 0.69 0.08 Ref 0.66 0.08 Ref
 Age, sex, education + SNSB (detailed) + T1b (thickness) 0.68 0.09 0.03 0.67 0.09 0.008 0.62 0.09  < 0.001
 Age, sex, education + SNSB (detailed) + T1 (texture) 0.71 0.08 0.06 0.71 0.08 0.12 0.70 0.08  < 0.001
 Age, sex, education + SNSB (detailed) + T1 (volume) 0.73 0.08  < 0.001 0.73 0.08  < 0.001 0.73 0.08  < 0.001
Step 3 Diffusion-tensor magnetic resonance image
 Age, sex, education + SNSB (detailed) + T1 (volume) 0.73 0.08 Ref 0.73 0.08 Ref 0.73 0.08 Ref
 Age, sex, education + SNSB (detailed) + T1 (volume) + DTI (FA) 0.73 0.08 0.60 0.73 0.08 0.42 0.73 0.08 0.85
 Age, sex, education + SNSB (detailed) + T1 (volume) + DTI (MD) 0.74 0.08 0.20 0.73 0.08 0.20 0.73 0.08 0.64

SD standard deviation, MMSE mini-mental state examination, SNSB Seoul neuropsychological screening battery, DTI diffusion-tensor image, FA functional anisotropy, MD mean diffusivity, Ref reference.