Table 2.
Within-group changes from pre-heading baseline in clinical and biochemical outcomes
| Variables | Group | 2 h Post (compared to baseline) | 24 h Post (compared to baseline) | 72 h Post (compared to baseline) |
|---|---|---|---|---|
| NPC (Unit in cm) | Cannabis user | 1.66 (0.99, 2.33) p < 0.001 | 1.88 (1.19, 2.57) p < 0.001 | 2.04 (1.34, 2.75) p < 0.001 |
| Non-user | 2.08 (1.3, 2.87) p < 0.001 | 3.11 (2.34, 3.88) p < 0.001 | 3.36 (2.59, 4.13) p < 0.001 | |
| S100B (Unit in pg/mL) | Cannabis user | −4.44 (−9.06, 0.17) p = 0.062 | 0.71 (−4.18, 5.6) p = 0.777 | 0.78 (−4.11, 5.67) p = 0.755 |
| Non-user | 4.95 (0.22, 9.68) p = 0.043 | 9.52 (4.79, 14.25) p < 0.001 | 12.49 (7.76, 17.22) p < 0.001 | |
| NfL (Unit in pg/mL) | Cannabis user | −0.25 (−0.61, 0.1) p = 0.164 | −0.09 (−0.46, 0.29) p = 0.656 | 0 (−0.37, 0.38) p = 0.992 |
| Non-user | −0.21 (−0.6, 0.17) p = 0.276 | 0.35 (−0.04, 0.73) p = 0.079 | 0.42 (0.04, 0.8) p = 0.034 |
Values expressed as difference from pre-heading baseline, followed by 95% confidence interval (low, high) and p value. NPC, near point of convergence. NfL, neurofilament light.