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. 2023 Jun 16;13:9797. doi: 10.1038/s41598-023-36704-1

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Compositional analyses at genus level of patients stratified for weight‐related and clinical features. Box plots indicate the median abundances and interquartile ranges of the taxa resulted statistically significant by ANCOM-BC test (*p-adj ≤ 0.05; **p-adj ≤ 0.01;). (A) comparisons between WBS normal weight and high weight; (B and C) comparisons between patients stratified for the presence of hypertension or not (abs. hypertension); (D) for absence (AoGiS) or presence of gastrointestinal symptoms (PoGiS) (constipation or diarrhoea); (E and F) for absence (AOS) or presence of at least 1 gastrointestinal symptom (POS) (gastroesophageal reflux disease, diarrhoea, constipation, abdominal pain).