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. 2023 Feb 25;43(5):951–964. doi: 10.1007/s10875-022-01426-y

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© The Author(s) 2023

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Fig. 3 — Patient 4: metabolic detoxification and lymphocyte levels throughout the study. Values obtained at Screening are indicated by a box shaded gray. Cut-off values for meeting full metabolic detoxification are indicated in the top panel by the horizontal dashed lines, colored to match the corresponding data set. Screening values were taken while patients were on pegademase and may not be trough values