Table 2.
Animal characteristics in each group at 14 weeks of age.
| Sham (N = 10) |
CKD (N = 10) |
AR 400 (N = 11) |
AR 800 (N = 12) |
|
|---|---|---|---|---|
| Body weight (g) | 503 ± 16 | 478 ± 10 | 478 ± 8 | 491 ± 6 |
| Residual kidney weight (g) | 1.64 ± 0.04 | 2.30 ± 0.16* | 2.01 ± 0.07* | 1.97 ± 0.08 |
| Heart weight (g) | 1.17 ± 0.03 | 1.20 ± 0.08 | 1.15 ± 0.04 | 1.15 ± 0.02 |
| Urine volume (ml/day) | 29.5 ± 4.0 | 45.8 ± 3.3* | 44.8 ± 2.1* | 40.3 ± 2.0* |
| Urinary sodium (mEq/day) | 3.11 ± 0.21 | 3.21 ± 1.1 | 3.30 ± 0.14 | 3.42 ± 0.13 |
| Urinary potassium (mEq/day) | 5.11 ± 0.37 | 4.76 ± 0.29 | 4.99 ± 0.24 | 5.23 ± 0.34 |
| Urinary protein (mg/day) | 18.9 ± 2.2 | 46.6 ± 10.7* | 24.7 ± 4.6# | 14.4 ± 2.2# |
*P < 0.05 vs. the sham group
#P < 0.05 vs. the CKD group
CKD chronic kidney disease, AR astragalus