. 2023 Jun 7;21:100300. doi: 10.1016/j.vas.2023.100300

Table 3.

Changes of oxidative stress indices (MDA, NO and GSH) at days 0, 3 and 7 in CPV-infected ill dogs treated with supportive treatment (ST) alone or ST with antioxidants (NAC, RES, CoQ10 and AA). The data have been reported as 75th percentile, and minimum and maximum values.

Groups (n = 9)	Day 0	Day 3	Day7
MDA (nM/mL)
ST	09.125^a	09.097^a	06.382^Ab
	(08.640–09.140)	(08.710–09.150)	(05.990–06.570)
ST+NAC	09.155^a	09.135^a	05.140^Bb
	(08.350–09.260)	(08.310–09.240)	(04.850–05.200)
ST+RES	09.177^a	09.157^a	05.175^Bb
	(08.620–09.350)	(08.630–09.330)	(04.870–05.190)
ST+CoQ10	09.345^a	09.325^a	06.377^Ab
	(08.240–09.750)	(08.260–09.730)	(05.990–06.550)
ST+AA	09.375^a	09.362^a	05.132^Bb
	(07.890–09.450)	(07.870–09.460)	(04.890–05.170)
NO (μM/mL)
ST	09.267^a	09.257^a	06.770^Ab
	(08.970–09.320)	(09.080–09.310)	(06.240–07.040)
ST+NAC	09.537^a	09.515^a	05.492^Bb
	(08.850–09.620)	(08.790–09.240)	(05.010–05.620)
ST+RES	09.392^a	09.500^a	05.557^Bb
	(08.980–09.520)	(08.630–09.560)	(04.960–05.640)
ST+CoQ10	09.545^a	09.825^a	06.870^Ab
	(08.620–10.550)	(08.470–10.230)	(05.970–07.050)
ST+AA	09.875^a	09.862^a	05.580^Bb
	(07.890–09.950)	(07.870–09.960)	(04.880–05.670)
GST (μmol/mL/min)
ST	0.932^a	0.942^a	0.657^Ab
	(0.790–0.940)	(0.820–0.950)	(0.530–0.680)
ST+NAC	0.965^a	0.947^a	0.475^Bb
	(0.810–0.980)	(0.780–0.970)	(0.410–0.490)
ST+RES	0.930^a	0.925^a	0.485^Bb
	(0.790–01.020)	(0.820–01.000)	(0.420–0.500)
ST+CoQ10	01.022^a	01.010^a	0.665^Ab
	(0.780–01.030)	(0.770–01.010)	(0.530–0.680)
ST+AA	0.920^a	0.927^a	0.487^Bb
	(0.790–0.980)	(0.820–0.980)	(0.410–0.510)

The 75th percentile values followed by the different uppercase letters (A, B) and lowercase letters (a, b) differ significantly among the groups and days, respectively at P = 0.05. MDA, malondialdehyde; NO, nitric oxide; GSH, glutathione S-transferase; ST, supportive treatment; NAC, N-acetylcysteine; RES, resveratrol; CoQ10, coenzyme Q10; AA, ascorbic acid.