Table 3.
Summary of regions that showed associations with baseline symptoms or symptom trajectories, while accounting for other cortical and subcortical regions
| Lobe | Psychotic-like experiences | Depressive symptoms | Anxiety symptoms | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Region | Metric | TPa | ↑↓b | Metric | TPa | ↑↓b | Metric | TPa | ↑↓b | |||
| Temporal | Transverse temporal | Thickness | Slope | ↑↑ | Middle temporal | Thickness | Baseline | ↑↑ | Entorhinal | Area | Baseline | ↑↑ |
| Fusiform | Thickness | Slope | ↑↓ | Inferior temporal | Thickness | Baseline | ↑↓ | Temporal pole | Area | Baseline | ↑↓ | |
| Middle temporal | Area | Slope | ↑↓ | Entorhinal | Area | Baseline | ↑↑ | Fusiform | Thickness | Slope | ↑↓ | |
| Parahippocampal | Area | Baseline | ↑↓ | |||||||||
| Occipital | Lateral occipital | Thickness | Slope | ↑↑ | ||||||||
| Parietal | Postcentral | Thickness | Baseline | ↑↓ | Precuneus | Thickness | Baseline | ↑↑ | ||||
| Inferior parietal | Thickness | Slope | ↑↓ | |||||||||
| Supramarginal | Area | Slope | ↑↑ | |||||||||
| Limbic | Posterior cingulate | Area | Baseline | ↑↑ | Isthmus cingulate | Thickness | Baseline | ↑↑ | ||||
| Posterior cingulate | Area | Baseline | ↑↑ | |||||||||
| Frontal | Precentral | Thickness | Baseline | ↑↓ | Superior frontal | Thickness | Baseline | ↑↓ | Superior frontal | Thickness | Baseline | ↑↓ |
| Superior frontal | Area | Baseline | ↑↓ | Precentral | Area | Baseline | ↑↓ | Caudal middle frontal | Thickness | Slope | ↑↑ | |
| Rostral middle frontal | Thickness | Slope | ↑↓ | |||||||||
Analysis timepoint.
Direction of the association, ↑↓ indicates that as thickness/area/volume goes down, symptoms increase, while ↑↑ indicates that as thickness goes up, symptoms go up.