Table 2.
Anaesthetic technique and perioperative drugs in patients randomized to receiving either propofol or sevoflurane for anaesthesia maintenance during the index procedure and any anaesthesia within one year before and one year after the index operation.
| Propofol |
Sevoflurane |
Total |
Missing |
|
|---|---|---|---|---|
| n (%) | n (%) | n (%) | % | |
| Anaesthesia time–min, median [IQR] | 120.0 [100.0, 145.0] | 125.0 [104.0, 152.0] | 123.0 [102.0, 149.0] | 0.0 |
| Anaesthesia with regional block/local | 531 (63.1) | 518 (62.5) | 1049 (62.8) | 0.0 |
| Infiltration | 0.0 | |||
| Paravertebral block | 66 (7.8) | 76 (9.2) | 142 (8.5) | |
| Intercostal block | 2 (0.2) | 1 (0.1) | 3 (0.2) | |
| Local infiltration | 443 (52.7) | 435 (52.5) | 878 (52.6) | |
| Anaesthesia, other | 51 (6.1) | 57 (6.9) | 108 (6.5) | 0.0 |
| Opioids, usage at index surgery | 0.0 | |||
| Oral opioids preop. | 398 (47.3) | 400 (48.3) | 798 (47.8) | |
| Fentanyl | 205 (24.4) | 576 (69.5) | 781 (46.8) | |
| Ketobemidone | 143 (17.0) | 130 (15.7) | 273 (16.3) | |
| Morphine | 123 (14.6) | 122 (14.7) | 245 (14.7) | |
| Remifentanil | 726 (86.3) | 349 (42.1) | 1075 (64.4) | |
| Sufentanil | 75 (8.9) | 71 (8.6) | 146 (8.7) | |
| Alfentanil | 3 (0.4) | 6 (0.7) | 9 (0.5) | |
| Opioids, dosage at index surgery | 0.0 | |||
| Oral opioids preop.–mg; median [IQR] | 5.0 [3.0–10.0] | 6.0 [3.0–10.0] | 5.3 [3.0–10.0] | |
| Fentanyl–μg; median [IQR] | 100.0 [100.0–150.0] | 100.0 [100.0–150.0] | 100.0 [100.0–150.0] | |
| Ketobemidone–mg; median [IQR] | 2.5 [2.5–5.0] | 2.5 [2.5–3.0] | 2.5 [2.5–5.0] | |
| Morphine–mg; median [IQR] | 4.0 [2.0–5.0] | 3.0 [2.0–5.0] | 4.0 [2.0–5.0] | |
| Remifentanil–μg; median [IQR] | 1032.0 [741.8–1450.0] | 805.8 [617.0–1072.5] | 952.0 [690.0–1304.0] | |
| Sufentanil–μg; median [IQR] | 26.2 [20.0–41.7] | 29.5 [21.6–40.1] | 28.6 [20.4–40.6] | |
| Alfentanil–mg; median [IQR] | 0.5 [0.5–1.3] | 0.5 [0.5–0.5] | 0.5 [0.5–0.5] | |
| Opioid usage postoperatively | 0.0 | |||
| Oral opioids postop. | 189 (22.5) | 162 (19.5) | 351 (21.0) | |
| Alfentanil | 1 (0.1) | 0 (0.0) | 1 (0.1) | |
| Fentanyl | 0 (0.0) | 9 (1.1) | 9 (0.5) | |
| Ketobemidone | 90 (10.7) | 64 (7.7) | 154 (9.2) | |
| Morphine | 106 (12.6) | 118 (14.2) | 224 (13.4) | |
| Meperidine | 1 (0.1) | 0 (0.0) | 1 (0.1) | |
| Remifentanil | 7 (0.8) | 1 (0.1) | 8 (0.5) |