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. 2023 Jun 9;60:102037. doi: 10.1016/j.eclinm.2023.102037

Table 2.

Anaesthetic technique and perioperative drugs in patients randomized to receiving either propofol or sevoflurane for anaesthesia maintenance during the index procedure and any anaesthesia within one year before and one year after the index operation.

Propofol
Sevoflurane
Total
Missing
n (%) n (%) n (%) %
Anaesthesia time–min, median [IQR] 120.0 [100.0, 145.0] 125.0 [104.0, 152.0] 123.0 [102.0, 149.0] 0.0
Anaesthesia with regional block/local 531 (63.1) 518 (62.5) 1049 (62.8) 0.0
Infiltration 0.0
 Paravertebral block 66 (7.8) 76 (9.2) 142 (8.5)
 Intercostal block 2 (0.2) 1 (0.1) 3 (0.2)
 Local infiltration 443 (52.7) 435 (52.5) 878 (52.6)
Anaesthesia, other 51 (6.1) 57 (6.9) 108 (6.5) 0.0
Opioids, usage at index surgery 0.0
 Oral opioids preop. 398 (47.3) 400 (48.3) 798 (47.8)
 Fentanyl 205 (24.4) 576 (69.5) 781 (46.8)
 Ketobemidone 143 (17.0) 130 (15.7) 273 (16.3)
 Morphine 123 (14.6) 122 (14.7) 245 (14.7)
 Remifentanil 726 (86.3) 349 (42.1) 1075 (64.4)
 Sufentanil 75 (8.9) 71 (8.6) 146 (8.7)
 Alfentanil 3 (0.4) 6 (0.7) 9 (0.5)
Opioids, dosage at index surgery 0.0
 Oral opioids preop.–mg; median [IQR] 5.0 [3.0–10.0] 6.0 [3.0–10.0] 5.3 [3.0–10.0]
 Fentanyl–μg; median [IQR] 100.0 [100.0–150.0] 100.0 [100.0–150.0] 100.0 [100.0–150.0]
 Ketobemidone–mg; median [IQR] 2.5 [2.5–5.0] 2.5 [2.5–3.0] 2.5 [2.5–5.0]
 Morphine–mg; median [IQR] 4.0 [2.0–5.0] 3.0 [2.0–5.0] 4.0 [2.0–5.0]
 Remifentanil–μg; median [IQR] 1032.0 [741.8–1450.0] 805.8 [617.0–1072.5] 952.0 [690.0–1304.0]
 Sufentanil–μg; median [IQR] 26.2 [20.0–41.7] 29.5 [21.6–40.1] 28.6 [20.4–40.6]
 Alfentanil–mg; median [IQR] 0.5 [0.5–1.3] 0.5 [0.5–0.5] 0.5 [0.5–0.5]
Opioid usage postoperatively 0.0
 Oral opioids postop. 189 (22.5) 162 (19.5) 351 (21.0)
 Alfentanil 1 (0.1) 0 (0.0) 1 (0.1)
 Fentanyl 0 (0.0) 9 (1.1) 9 (0.5)
 Ketobemidone 90 (10.7) 64 (7.7) 154 (9.2)
 Morphine 106 (12.6) 118 (14.2) 224 (13.4)
 Meperidine 1 (0.1) 0 (0.0) 1 (0.1)
 Remifentanil 7 (0.8) 1 (0.1) 8 (0.5)