Table 3.
All (N = 8610) |
Alirocumab (N = 4305) |
Placebo (N = 4305) |
|
---|---|---|---|
LDL-C, mmol/L | 2.1 ± 0.6 | 2.1 ± 0.6 | 2.16 ± 0 |
Non-HDL-C, mmol/L | 2.9 ± 0.7 | 2.9 ± 0.7 | 2.9 ± 0.7 |
Total cholesterol, mmol/L | 4.0 ± 0.8 | 4.0 ± 0.8 | 4.0 ± 0.8 |
HDL-C, mmol/L | 1.1 ± 0.3 | 1.1 ± 0.3 | 1.1 ± 0.3 |
Fasting triglycerides, mmol/L | 1.8 ± 1.0 | 1.8 ± 1.0 | 1.8 ± 1.1 |
Lipoprotein(a), mg/dL | 28.6 ± 33.1 | 28.7 ± 33.3 | 28.7 ± 33.2 |
Apolipoprotein B, mg/dL | 77.6 ± 17.3 | 78.1 ± 17.5 | 77.9 ± 17.4 |
Apolipoprotein A1, mg/dL | 131.6 ± 23.0 | 131.2 ± 22.5 | 131.4 ± 22.7 |
Apolipoprotein B/Apolipoprotein A1 ratioa | 0.61 ± 0.2 | 0.61 ± 0.2 | 0.61 ± 0.2 |
Total cholesterol/HDL-C ratioa | 3.8 ± 1.0 | 3.8 ± 1.0 | 3.8 ± 1.0 |
Data are presented as mean ± SD
HDL-C High-density lipoprotein cholesterol, LDL-C Low-density lipoprotein cholesterol, Q Quartile, SD Standard deviation
a Ratios were only calculated if the 2 samples were collected at the same visit