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. 2023 Jun 16;23:279. doi: 10.1186/s12886-023-03012-1

Table 3.

Baseline lipid parameters in patients on alirocumab with ≥ 2 consecutive LDL-C values < 25 mg/dL and propensity score-matched patients on placebo

All
(N = 8610)
Alirocumab
(N = 4305)
Placebo
(N = 4305)
LDL-C, mmol/L 2.1 ± 0.6 2.1 ± 0.6 2.16 ± 0
Non-HDL-C, mmol/L 2.9 ± 0.7 2.9 ± 0.7 2.9 ± 0.7
Total cholesterol, mmol/L 4.0 ± 0.8 4.0 ± 0.8 4.0 ± 0.8
HDL-C, mmol/L 1.1 ± 0.3 1.1 ± 0.3 1.1 ± 0.3
Fasting triglycerides, mmol/L 1.8 ± 1.0 1.8 ± 1.0 1.8 ± 1.1
Lipoprotein(a), mg/dL 28.6 ± 33.1 28.7 ± 33.3 28.7 ± 33.2
Apolipoprotein B, mg/dL 77.6 ± 17.3 78.1 ± 17.5 77.9 ± 17.4
Apolipoprotein A1, mg/dL 131.6 ± 23.0 131.2 ± 22.5 131.4 ± 22.7
Apolipoprotein B/Apolipoprotein A1 ratioa 0.61 ± 0.2 0.61 ± 0.2 0.61 ± 0.2
Total cholesterol/HDL-C ratioa 3.8 ± 1.0 3.8 ± 1.0 3.8 ± 1.0

Data are presented as mean ± SD

HDL-C High-density lipoprotein cholesterol, LDL-C Low-density lipoprotein cholesterol, Q Quartile, SD Standard deviation

a Ratios were only calculated if the 2 samples were collected at the same visit