Table 7.

Demographic details, anatomical and functional outcomes of eyes which have undergone MICOF keratoprosthesis (including >15 eyes)

Authors, year	No. of eyes	Mean age (years, range)	Follow-up duration (range), months	Etiology No. of eyes (%)	Anatomical success No. of eyes (%)	Functional outcome	Complications No. of eyes (%)
Huang et al.[37] 2011	85	44.9 (19-80)	34.7 (3-107)	Alkali burns: 39 (45.9%) Thermal burn: 20 (23.5%) Acid burn: 1 (12.9%) SJS: 10 (11.8%) MMP: 5 (5.9%)	69/85 (81.2%)	NA	RPM: 39 (45.9%) Corneal leak/melt: 16 (19%)
Huang et al.[38] 2012	14	67 (29-80)	46.8 (10-93.6)	SJS: 7 (50%) MMP: 4 (28.5%) Sjogren’s: 3 (21.4%)	14/14 (100%)	BCVA ≥20/200 Achieved: 13/14 (93%) Maintained: 9/13 (69%) BCVA ≥20/40: Achieved: 43% Maintained: none	Corneal leak/melt: 7 (50%) Conjunctival membrane overgrowth: 2 (14%)
Wang et al.[39] 2015	90	40 (8-64)	58.22 (1-145)	Alkali burns: 51 (56.6%) Acid burns: 18 (20%) Thermal burns: 21 (23.33%)	87/90 (96.67%)	BCVA ≥20/200 Achieved: 73/90 (81.11%) Maintained: NA BCVA ≥20/40: Achieved: 39/90 (43.33%) Maintained: NA	Corneal leak/melt: 36 (40%) Conjunctival membrane overgrowth: 28 (31.11%)
Ma et al.[40] 2017	14	61.5 (27-87)	62 (13-144)	SJS: 14 (100%)	13 (92.8%)	BCVA ≥20/200 Achieved: 13/14 (92.9%) Maintained: 10/14 (71.4%) BCVA ≥20/40: Achieved: 8/14 (57.1%) Maintained: 5 (35.7%)	Corneal leak or melt: 10 (71.4%) RPM: 4 (28.6%)
Wang et al.[41] 2021	91	46.7 (17-90)	100.56 (60-207)	Chemical or thermal burns: 62 (68.1%) Explosive injuries: 11 (12.1%) SJS: 9 (10.0%) Sjogren’s syndrome: 4 (4.4%) MMP: 3 (3.3%) Multiple failed PK: 2 (2.2%)	77/91 (84.6%)	BCVA ≥20/200 Achieved: 41/90 (45%) Maintained: 32/91 (35.2%)	Conjunctival membrane overgrowth: 29 (31.9%) RPM: 14 (15.4%)

BCVA=best-corrected visual acuity, MICOF=the Moscow eye microsurgery complex in Russia, MMP=mucous membrane pemphigoid, NA=not applicable, PK=penetrating keratoplasty, RD=retinal detachment, RPM=retroprosthetic membrane, SJS=Stevens-Johnson syndrome