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. 2023 Jun 17;14:3605. doi: 10.1038/s41467-023-39292-w

Fig. 6. Derivation of the pseudo-virus neutralization titer decay curves for casirivimab + imdevimab mAb combination.

Fig. 6

A Ten randomly selected population PK predicted casirivimab + imdevimab mAb combined antibody serum concentration vs time curves as a function of days since injection. B 18 paired measurements, sampled throughout the course of follow-up (black dots) were used to estimate a linear relationship (black line). A day 150 population PK predicted mAb concentration (turquoise dot) thus results in a predicted ID50 (turquoise triangle). The predicted ID50s were used to generate neutralization titer decay curves (Panel C).