Table 6.

Differences in QST parameters (indicated by effect size) by contextual laboratory factors for acute MSK pain among youth

QST parameter	Momentary pain^a: Yes (86) vs. No (191)	On menstrual period^b: Yes (18) vs. No (116)	Medication use^c: Yes (15) vs. No (262)
Pressure pain threshold (forearm, log₁₀)	−0.14	−0.37	0.16
Pressure pain threshold (trapezius, log₁₀)	0.09	−0.63	0.19
Heat pain threshold	−0.18	0.14	0.02
Cold pain tolerance (ss)	0.01	−0.07	0.06
Cold pain rating	−0.00	0.19	0.03
Painful after-sensations	0.15	0.35	−0.03
Temporal summation of pain	−0.13	0.04	−0.49
Conditioned pain modulation index	0.31	−0.17	−0.45

QST = quantitative sensory testing; MSK = musculoskeletal.

Momentary pain refers to a “yes” answer to the question: “Are you in any pain right now” asked right before QST assessment.

Analyses were performed for girls who already had their first menstrual period.

Medication included Ibuprofen, Acetaminophen, and Naproxen.