Table 1.

Diagnostic criteria for drug-induced Sweet syndrome (DISS) (4, 5).

1. Abrupt onset of painful erythematous plaques or nodules

2. Histopathological evidence of dense neutrophilic infiltration without evidence of vasculitis

3. Pyrexia, >38°C

4. Temporal relationship between drug ingestion and clinical presentation, or temporally related recurrence after oral challenge

5. Temporally related resolution of lesions after drug withdrawal or treatment with systemic corticosteroids