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. 2023 Jun 5;14:1193808. doi: 10.3389/fimmu.2023.1193808

Table 2.

Major and minor diagnostic criteria for Sweet syndrome.

Criteria Findings
Major 1. Abrupt onset of painful erythematous plaques or nodules
2. Histopathological evidence of a dense neutrophilic infiltrate without evidence of leukocytoclastic vasculitis
Minor 1. Pyrexia, >38°C
2. Association with an underlying hematological or visceral malignancy, inflammatory disease, or pregnancy; or preceded by an upper-respiratory or gastrointestinal inflection or vaccination
3. Excellent response to treatment with systemic corticosteroids or potassium iodide
4. Abnormal laboratory values at presentation (three or four): *Erythrocyte sedimentation rate (ESR) > 20 mm/h *White blood cell count (WBC) > 8×109/L *Neutrophil count > 70% *High C-reactive protein (CRP) levels