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. 2023 Jun 13;4(3):102348. doi: 10.1016/j.xpro.2023.102348

Table 5.

An example 24-well plate setup for evaluating the ability of 12 candidate antidote oligonucleotides 1–12 (A1-A12) to reverse the binding of the E07 EGFR-targeting aptamer to EGFR on cells

1 2 3 4 5 6
A Cells alone Cells + C36 nontargeting control Cells + E07 Cells + A1 → E07 Cells + A2 → E07 Cells + A3 → E07
B Cells + A4 → E07 Cells + A5 → E07 Cells + A6 → E07 Cells + A7 → E07 Cells + A8 → E07 Cells + A9 → E07
C Cells + A10 → E07 Cells + A11 → E07 Cells + A12 → E07
D