Table 5.
Correlational analysis between altered FCs with PANSS and cognitive scores.
| Clinical variable | ROI–ROI/ network–network (*) connection | r | P |
|---|---|---|---|
| PANSS_P | PREC (R)–aHIPPO (R) | −0.249 | 0.021 |
| PANSS_N | aHIPPO–AT* | −0.298 | 0.005 |
| AMYG (L)–pHIPPO (L) | −0.231 | 0.033 | |
| PANSS_T | PHC (R)–PREC (L) | 0.229 | 0.034 |
| PHC (R)–PREC (R) | 0.223 | 0.039 | |
| AV | PHC (R)–PREC (R) | −0.227 | 0.036 |
| Vis_Lrng | PRC (R)–OFC (L) | 0.271 | 0.012 |
| Verbl_Lrng | PRC (R)–OFC (L) | 0.506 | 0.000 |
| PRC (R)–OFC (R) | 0.409 | 0.000 | |
| WM | OFC (L)–pHIPPO (L) | 0.297 | 0.006 |
| PRC (R)–OFC (L) | 0.284 | 0.009 | |
| RPS | aHIPPO–pHIPPO* | 0.236 | 0.029 |
| AMYG (L)–pHIPPO (L) | 0.214 | 0.048 | |
| PHC (R)–PREC (L) | 0.252 | 0.020 | |
| PRC (R)–OFC (L) | 0.225 | 0.038 | |
| SC | aHIPPO–pHIPPO* | −0.226 | 0.037 |
| aHIPPO–PM* | −0.315 | 0.003 | |
| ANG (L)–aHIPPO (R) | −0.299 | 0.005 | |
| PHC (R)–PREC (L) | −0.279 | 0.009 | |
| PHC (R)–PREC (R) | −0.219 | 0.043 | |
| PREC (L)–aHIPPO (R) | −0.313 | 0.003 | |
| PREC (R)–aHIPPO (R) | −0.293 | 0.006 |
PREC, precuneus; AMYG, amygdala; pHIPPO, posterior hippocampus; aHIPPO, anterior hippocampus; PHC, parahippocampal cortex; OFC, orbitofrontal cortex; PRC, perirhinal cortex; RSC, retrosplenial cortex; PCC, posterior cingulate cortex; ANG, angular gyrus; L, left; R, right; ROI, region of interest; PM, posterior medial system; AT, anterior temporal system; PANSS_P, positive PANSS score; PANSS_N, negative PANSS score; PANSS_T, total PANSS score; SOP, speed of processing; AV, attention/vigilance; WM, working memory; Vrbl_Lrng, verbal learning and memory; Vis_Lrng, visual learning and memory; RPS, reasoning and problem-solving; SC, social cognition.
represent between network FC alterations.