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. 2023 Jun 5;13:1156743. doi: 10.3389/fonc.2023.1156743

Table 1.

Immunophenotyping of B lymphoproliferations arising in a NSCLC xenograft program.

Patient Region CD20 CD79A CD3 BCL2 CD56 CD10 BCL6 MUM1 CD138 CD30 EBER Ig
CRUK0701 R1 + + # + - - # + # + + K
CRUK0704 T1 IR + + # + - - # + # + + L (K)
CRUK0731 IR + + # + - - # + # + + K
CRUK0764 IR + + - + - - # + # + + L
CRUK0795 IR + + # + - - # + # + + L (K)
CRUK0825 R7 + + + + - - # + # + + K
CRUK0830 R4 + + # + # - # + # + + K (L)
CRUK0934 R6 + + - + - - # + # + + K
CRUK0941 R1 + + # + - - # + # + + K (L)
CRUK0949 R6 + + + + - - # + # + + K
CRUK0810 R4 + + - + - - # + # + + K
R8 + + # + - - # + # + + L (K)
CRUK1054 R2 + + # + - - # + # + + K
R5 + + - + - - # + # + + L
CRUK0733 R5 + + # + - - # + # + + K
R1 Histology sample unavailable

IR, inter-region (i.e. not matched to a tumour region defined within the lung TRACERx study). + Detected in the majority of cells; # Detected in a subset of cells. Detection of both IgK and IgL light chain expression by immunohistochemistry is indicated with the minor light chain shown in brackets.