. 2023 Jun 5;14:1187261. doi: 10.3389/fendo.2023.1187261

Table 4.

Endothelial disfunction and lipidic profile modifications.

ENDOTHELIAL DISFUNCTION AND LIPIDIC PROFILE MODIFICATIONS
•Birth weight is associated with impaired endothelial function in childhood and adulthood •Prenatal growth restraint results in cardiovascular remodeling, and this may intensify the predisposition for future cardiovascular disease •Aortic and carotid IMT are increased in SGA children and adults •Excessive weight gain between 3 and 6 years of age is an independent predictor of carotid IMT •Obesity-related increase of carotid IMT has been reported since childhood and adolescence, and it persists in adulthood if obesity is not corrected on time •Higher IMT is associated also with preterm birth
•Dyslipidemia has an important impact on cardio-metabolic health •Being born SGA is related to an unfavorable lipid profile in childhood and adolescence •Poor catch-up growth in height is associated with high levels of total cholesterol in adolescence •LBW has been associated with onset of dyslipidemia also in adulthood •Preterm birth is associated with higher triglycerides levels in childhood and higher total cholesterol levels in adult life

ENDOTHELIAL DISFUNCTION AND LIPIDIC PROFILE MODIFICATIONS

•Birth weight is associated with impaired endothelial function in childhood and adulthood
•Prenatal growth restraint results in cardiovascular remodeling, and this may intensify the predisposition for future cardiovascular disease
•Aortic and carotid IMT are increased in SGA children and adults
•Excessive weight gain between 3 and 6 years of age is an independent predictor of carotid IMT
•Obesity-related increase of carotid IMT has been reported since childhood and adolescence, and it persists in adulthood if obesity is not corrected on time
•Higher IMT is associated also with preterm birth

•Dyslipidemia has an important impact on cardio-metabolic health
•Being born SGA is related to an unfavorable lipid profile in childhood and adolescence
•Poor catch-up growth in height is associated with high levels of total cholesterol in adolescence
•LBW has been associated with onset of dyslipidemia also in adulthood
•Preterm birth is associated with higher triglycerides levels in childhood and higher total cholesterol levels in adult life

IMT, Intima-Media Thickenss; LBW, Low-Birth Weight; SGA, Small for Gestational Age.