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. 2022 Mar 28;53(8):3426–3436. doi: 10.1017/S0033291721005493

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© The Author(s) 2022

This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.

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Fig. 4. — Results of the whole-brain voxelwise mixed model of the reward feedback phase. Left: Significant three-way interaction of group × depletion condition × reward level within the mOFC (x = 5). FWE corrected with p < 0.05. Right: Mean activation in each group for each reward level (β estimates plus a smooth regression line) in the mOFC during the reward feedback phase during both time points (ATD and sham depletion). mOFC = medial orbitofrontal cortex; DEPL = acute tryptophan depletion; SHAM = sham depletion; recAN = individuals with a history of AN; HC = healthy control participants; BOLD = blood oxygen level dependent.