Table 3.

Change in quality of life measured with quality of life in reflux and dyspepsia instrument (QOLRAD)

Domain	Mean difference in change in quality of life (eradication arm−placebo arm)*	Range	P value
Emotional distress	0.34	0.04-0.65	0.03
Sleep disturbance	0.18	−0.10-0.46	0.21
Problems with eating or drinking	0.20	−0.10-0.50	0.20
Physical and social functioning	0.25	0.01-0.48	0.04
Vitality	0.39	0.08-0.70	0.02

^*A positive value indicates greater symptom improvement in the eradication arm.