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. 2023 Jun 5;10:1186574. doi: 10.3389/fcvm.2023.1186574

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© 2023 Raposo, Cerqueira, Leite, Moreira-Costa, Laundos, Miranda, Mendes-Ferreira, Coelho, Gomes, Pinto-do-Ó, Nascimento, Lourenço, Cardim and Leite-Moreira.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Doppler-derived coronary flow velocity. At the end of the injection, APV was higher in vehicle injected animals (with and without MI), as compared to hUCM-MSC (26.8 ± 6.8 vs. 20.5 ± 4.5; ANOVA p = 0.03). In infarcted animals injected with hUCM-MSC, final APV did not decrease significantly as compared do baseline (20.3 ± 4.5 vs. 21.5 ± 3.6; Related samples Wilcoxon Signed rank test p = 0.25). Symbols represent geometric means and bars represent standard deviation. APV, average peak velocity; T1/2—half time injection.