Skip to main content
. 2023 Feb 28;31(6):1846–1856. doi: 10.1016/j.ymthe.2023.02.018

Figure 1.

Figure 1

The ROCK inhibitor ripasudil enhances hepatocyte liver engraftment

(A) C57 mice were transplanted with luciferase-expressing hepatocytes. The effects of the ROCK inhibitor ripasudil, nonmuscle myosin II ATPase inhibitor blebbistatin, β1-integrin agonist pyrintegrin, and Src kinase inhibitor dasatinib on hepatocyte liver engraftment were analyzed by bioluminescence imaging on days 3 and 5 after intrasplenic infusion. (B and C) Quantification of bioluminescence imaging of mice on days 3 and 5 after hepatocyte transplantation. Data are shown as the means ± SEMs (n = 3). ∗p < 0.05.