Table 3.

Biosafety infrastructure priorities

Biosafety infrastructure priorities
Human factor
Training	• GMPP including regular updates on new information.
	• Awareness of “dual use” or “gain of function” research and the adverse implications of these activities
Reliability and competency	• Best practice for demonstrating or assessing human reliability including quantitative measures of reliability
	• Demonstrating the connection between reliability, quality, and biosafety
	• What is the best way to determine competency with infectious materials in the laboratory?
Cumbersome risk mitigation	• How to work safely—maybe the implementation of risk mitigation strategies makes matters worse as it does not allow easy working
Workforce development	• Development of biosafety as a vocation supported by locally available and relevant training.
Lack of biocontainment engineers	• Train the next generation of biocontainment engineers that will be able to provide sustainability to these facilities as well as to advise on requirements for future facilities
Biosafety administration
Laboratory-acquired infection and escapes	• Development and implementation of a global laboratory-acquired infection or laboratory escape reporting system.
Registration of laboratories	• Regulation of laboratories worldwide especially those containing highly pathogenic agents
IBCs	• Develop a culture of IBCs to regulate and review biosafety matters within institutions.
Biosecurity and repositories	• Ensure there is a standardized and regulated method of storing pathogens using basic biorepository principles.
Pathogen-based issues
Pathogen risk groups	• Opportunity to review the value of pathogen risk groups

GMPP, good microbiological practices and procedures; IBCs, institutional biosafety committees.