TABLE 3.

Effects of depression on pain, fatigue, and c-reactive protein (CRP)

	B	SE	β	R2	ΔR2
Pain
Block 1				0.06
Age	−0.03	0.02	−0.16
Sex	0.75	0.62	0.14
BMI	0.004	0.04	0.01
Stage	−0.06	0.12	−0.06
Comorbidities
Block 2				0.12	0.06
Depression	0.07	0.03	0.27*
Fatigue
Block 1				0.24
Age	−0.54	0.17	−0.38**
Sex	1.02	4.48	0.02
BMI	0.29	0.27	0.12
Stage	−0.35	0.86	−0.04
Comorbidities	3.76	1.12	0.41**
Block 2				0.69	0.45**
Depression	1.51	0.15	0.75***
CRP
Block 1				0.17
Age	−0.002	0.01	−0.02
Sex	−0.02	0.24	−0.10
BMI	0.04	0.02	0.32*
Stage	0.13	0.05	0.30**
Comorbidities	0.23	0.15	0.20
Block 2				0.23	0.07*
Depression	0.03	0.01	0.29*

Abbreviations: ΔR² = change in R2; B = standardized beta; SE = standard error; b = unstandardized beta.

^*p < 0.05,

^**p < 0.01.