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. Author manuscript; available in PMC: 2023 Jun 19.
Published in final edited form as: Cell Rep. 2023 Apr 26;42(5):112435. doi: 10.1016/j.celrep.2023.112435

Figure 4. PDM-LD association promotes lipid synthesis.

Figure 4.

(A) Schematic of the experimental design using [1-14C]oleate or acetate as the substrate to assess FA incorporation into complex lipids from samples isolated from fasted mice.

(B) Representative thin-layer chromatography (TLC) of lipids extracted from liver homogenates, LDs, and mitochondrion-LD incubations.

(C) [1-14C]oleate incorporation into PL, DAG, TAG, and CE. n = 3 independent isolations.

(D) [1-14C]acetate incorporation into PL, TAG, and FA. n = 3.

(E) [1-14C]oleate incorporation into LDs co-incubated with CM and PDM isolated from control or PLIN5 KD fasted animals. n = 4.

ns, p > 0.05; *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.