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. 2022 Apr 30;13(2):385–392. doi: 10.34172/apb.2023.022

Table 1. Cytotoxicity of Lipofectamine/dendrimer and short RNA complex reported in some other studies compared to ours .

Cell line Volume in 500 μL Viability (%) compared to blank Ref.
T47D 0.4 μL Lipofectamine 98.5 This study
0.75 μL Lipofectamine 88.5
PAMAM G5 N/P = 10 92.5
PAMAMG5 N/P = 20 88.5
PAMAMG5 N/P = 40 74.5
MCF-10A 0.4 μL Lipofectamine 99
0.75 μL Lipofectamine 99
T47D PAMAM G2, G3, G4 and G5 Toxic at the higher generations 28
HEK293 1.5 μL Lipofectamine No apparent toxic effect 15
SW480 2 μL Lipofectamine Without significant toxicity 31
Huh-7 2 μL Lipofectamine 75.34 16
HEK2 87.29
MCF-7 92.49
U87MG 80