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. 2023 Apr 27;12(11):12912–12928. doi: 10.1002/cam4.5942

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© 2023 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Functional enrichment characteristics based on the ERG signature stratification. (A) Volcano plot of DEGs between high‐ and low‐ERG‐score groups. Red plots represent statistically significant DEGs (|logFC| > 0.5 and adjust.p < 0.05). (B) Heatmap of statistically significant DEGs between high‐ and low‐ERG‐score groups. Pivotal items of GO (C) and KEGG (D) enrichment analyses based on the marker genes (logFC >0.5 and adjust.p < 0.05) in high‐ and low‐ERG‐score groups. Heatmaps of GSVA analysis for ERG signature subgroups based on GO‐biological‐process (E) and KEGG (F) gene sets in the MSigDB database.