Table 1.
Baseline characteristics by trajectory of Beck Depression Inventory Score
| Variables | Persistently Low Beck Depression Inventory Score (n=1363) | Persistently Moderate Beck Depression Inventory Score (n=782) | Persistently High Beck Depression Inventory Score (n=216) | P Value |
|---|---|---|---|---|
| Age, yr, mean (SD) | 58.6 (10.4) | 58.5 (10.2) | 55.5 (9.4) | 0.0001 |
| Age <50 yr, % | 239 (17.5) | 147 (18.8) | 55 (25.5) | 0.02 |
| Sex, female, % | 580 (42.6) | 396 (50.6) | 133 (61.6) | <0.0001 |
| Race, % | <0.0001 | |||
| Non-Hispanic White | 739 (54.2) | 341 (43.6) | 76 (35.2) | |
| Non-Hispanic Black | 473 (34.7) | 326 (41.7) | 101 (46.8) | |
| Hispanic | 151 (11.1) | 115 (14.7) | 39 (18.1) | |
| Less than high school, % | 140 (10.3) | 160 (20.5) | 58 (26.9) | <0.0001 |
| No health insurance, % | 56 (4.1) | 61 (7.8) | 26 (12.0) | <0.0001 |
| Current smoker, % | 95 (7.0) | 95 (12.2) | 53 (24.5) | <0.0001 |
| Alcohol use, % | 947 (69.5) | 501 (64.1) | 123 (56.9) | 0.0003 |
| Any activities with MET score ≥6, % | 441 (32.4) | 156 (20.0) | 30 (13.9) | <0.0001 |
| Diabetes, % | 512 (37.6) | 372 (47.6) | 111 (51.4) | <0.0001 |
| Systolic BP, mean (SD), mmHg | 123.8 (19.2) | 125.5 (20.4) | 125.9 (19.6) | 0.08 |
| Diastolic BP, mean (SD), mmHg | 70.8 (12.0) | 69.8 (12.2) | 71.4 (11.1) | 0.12 |
| Cardiovascular disease, % | 330 (24.2) | 278 (35.6) | 92 (42.6) | <0.0001 |
| BMI ≥30 kg/m2, % | 697 (51.1) | 473 (60.5) | 142 (65.7) | <0.0001 |
| Quality of life—physical composite, mean (SD) | 46.3 (10.1) | 39.0 (11.5) | 33.7 (9.9) | <0.0001 |
| Quality of life—mental composite, mean (SD) | 55.3 (6.66) | 47.6 (10.1) | 36.2 (9.6) | <0.0001 |
| eGFR, mean (SD), ml/min per 1.73 m2 | 46.7 (14.33) | 44.3 (15.2) | 43.3 (15.3) | <0.0001 |
| Hemoglobin, mean (SD), mg/dl | 13.0 (1.7) | 12.7 (1.6) | 12.4 (1.6) | <0.0001 |
| 24H urine protein, median, g/24H | 0.11 | 0.13 | 0.19 | <0.0001 |
| High sensitivity CRP, mean (SD), mg/L | 4.6 (8.0) | 5.7 (10.1) | 6.2 (10.3) | 0.003 |
| ACEI/ARB use, % | 934 (68.5) | 552 (70.6) | 130 (60.2) | 0.01 |
| Antidepressant use, % | 149 (10.9) | 198 (25.3) | 95 (44.0) | <0.0001 |
BMI, body max index; MET, metabolic equivalent of task; CRP, C-reactive protein; ACEI/ARB, angiotensin-converting enzyme inhibitor/angiotensin receptor blocker.