Comparison 9. Fixed versus ad lib dose schedule.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
9.1 Smoking cessation	4	828	Risk Ratio (M‐H, Fixed, 95% CI)	1.12 [0.87, 1.45]
9.1.1 Gum	2	689	Risk Ratio (M‐H, Fixed, 95% CI)	1.22 [0.92, 1.61]
9.1.2 Nasal spray	2	139	Risk Ratio (M‐H, Fixed, 95% CI)	0.67 [0.35, 1.30]
9.2 Overall serious adverse events	1		Risk Ratio (M‐H, Fixed, 95% CI)	Totals not selected
9.3 Treatment withdrawals	2		Risk Ratio (M‐H, Fixed, 95% CI)	Totals not selected
9.3.1 Gum	1		Risk Ratio (M‐H, Fixed, 95% CI)	Totals not selected
9.3.2 Nasal spray	1		Risk Ratio (M‐H, Fixed, 95% CI)	Totals not selected