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. 2023 Jun 19;2023(6):CD013308. doi: 10.1002/14651858.CD013308.pub2

Comparison 13. Other comparisons.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
13.1 Smoking cessation 6   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
13.1.1 24‐hour versus 16‐hour patch 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
13.1.2 50 weeks versus 10 weeks gum 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
13.1.3 Continue versus stop patch use on lapse 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
13.1.4 35 mg patch + fast‐acting for 22 weeks versus 21 mg patch for 10 weeks 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
13.1.5 NRT tester period + choice versus clinician‐advised 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
13.1.6 100% nicotine dose substitution based on weekly saliva cotinine concentration versus nicotine patch with monthly dose decreases plus gum or lozenge at investigator discretion  1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
13.2 Midsternal pressure 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
13.2.1 50 weeks versus 10 weeks gum 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
13.3 Cardiac adverse events 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
13.4 Chest pain 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
13.5 Palpitations 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
13.6 Overall serious adverse events 5   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
13.6.1 50 weeks versus 10 weeks gum 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
13.6.2 Continue versus stop patch use on lapse 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
13.6.3 35 mg patch + fast‐acting for 22 weeks versus 21 mg patch for 10 weeks 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
13.6.4 NRT tester period + choice versus clinician advised 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
13.6.5 100% nicotine dose substitution adapted based on weekly saliva cotinine concentration versus monthly decreases in nicotine dose  1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
13.7 Treatment withdrawals 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected
13.7.1 35 mg patch + fast‐acting for 22 weeks versus 21 mg patch for 10 weeks 1   Risk Ratio (M‐H, Fixed, 95% CI) Totals not selected