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. 2023 Jun 19. Online ahead of print. doi: 10.1016/S0140-6736(23)00917-0

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Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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The Crick COVID Testing Pipeline mirrors the dynamics of the first year of the COVID-19 pandemic in London

(A) Prevalence of all SARS-CoV-2 infections in cases per 1000 residents, by London borough from April, 2020, to May, 2021. (B) Numbers of daily tests conducted by the CCTP from April, 2020, to April, 2022. (C) Rolling 7-day incidence of SARS-CoV-2 infections across all the CCTP sites from April, 2020, to May, 2021. Vertical lines indicate peak daily positive tests, smoothed lines indicate 7-day rolling mean. (D) SARS-CoV-2 lineage positive PCR tests as a monthly proportion of total positive tests from April, 2020, to March, 2022. (E) Phylogenetic tree showing variation in all SARS-CoV-2 lineages isolated by the CCTP between 2020 and 2022, and coloured according to variants of concern. (F) Detection lead time in days for three variants of concern related to WHO designation date. CCTP=Crick COVID Testing Pipeline. Crick=Francis Crick Institute. CNWL=Camden and Northwest London NHS Trust. NMUH=North Middlesex University Hospital. NWP=Northwick Park Hospital. RFH=Barnet and Royal Free Hospitals. UCLH=University College London Hospitals.