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. 2022 Feb 11;2022:2014568. doi: 10.1155/2022/2014568

Figure 8.

Figure 8

Schematic representation of KAT5 inhibitor NU9056 suppresses ATC progression via c-Myc/miR-202 pathway. In ATC cells, elevated KAT5 increases transcription factor c-Myc expression by promoting its protein stabilization. C-Myc then activates miR-202-5p transcription and mediates ATC progression. NU9056 inhibits ATC progression via the blockade of KAT5/c-Myc/miR-202 pathway.