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. 2023 Jun 19;10:29. doi: 10.1186/s40580-023-00377-3

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Ultrafast wide-field, high-resolution, functional OR-PAM for the study of ischemic stroke. a Schematic of the ultrafast functional PAM. The 532 nm light source and 558 nm Raman source are combined for functional imaging. Inset illustrates the UT, polygon scanner, laser, and scanning range. b Propagation time map of the SD wave and changes in PA intensity and SO₂ during the SD wave propagation at different time steps. PAM, photoacoustic microscopy; DM, dichroic mirror; UT, ultrasound; SO₂, oxygen saturation; PA, photoacoustic; SD, spreading depolarization. The images are reproduced with permission from [83]