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. 2023 Jun 6;14:1142680. doi: 10.3389/fphar.2023.1142680

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Copyright © 2023 Cairns, Benson, Bedoya-Pérez, Macphail, Mohan, Cohen, Sachdev and McGregor.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Approvals per month in psychiatric indications with >100 approvals. Approvals over time for anxiety [(A), n = 67,095]; sleep disorder [(B), n = 11,202)], insomnia [(C), n = 6,877); post-traumatic stress disorder [PTSD; (D), n = 5,799]; depression [(E), n = 3,247]; autism spectrum disorder [ASD; (F), n = 2,206]; attention deficit hyperactivity disorder [ADHD; (G), n = 2,078]; mood disorder [(H), n = 736]; Alzheimer’s disease [(I), n = 272]; restless leg syndrome [RLS; (J), n = 239]; bipolar disorder [(K), n = 212]; Tourette’s syndrome [(L), n = 163]; unspecified dementia [(M), n = 132]; behavior disorder [(N), n = 131]; cannabis use disorder [(O), n = 117]. Solid lines represent the best fit, with shading depicting standard error of the mean (SEM).