Table 3.
Summary of microcrystal preparation.
| Sr.No | Preparation method | w/v of solvent | Method of dissolution | Condition | Dissolving agent | |
|---|---|---|---|---|---|---|
| Embodiment 1 | Drug dissolved in separate organic solvent acetonitrile, dehydrated alcohol, acetone | 1 g:1 mL | Ultrasonic dissolution | cool to room temperature | Hydrochloric acid or acetic acid. |  |
| Embodiment 2 | combination of any two solvents acetonitrile, dehydrated alcohol, acetone | 1 g:10 mL | Ultrasonic dissolution | |||
| Embodiment 3 | combination of three kinds in acetonitrile, dehydrated alcohol, acetone | 1 g:40 mL | Heating for dissolving at 30 °C | |||
| Embodiment 4 | combination of acetonitrile, dehydrated alcohol, acetone | 1 g:60 mL | Heating for dissolving at 80 °C | |||
| Embodiment 5 | acetonitrile, dehydrated alcohol, acetone | 1 g:50 mL | heating for dissolving at 50 °C |