Table 8.
Summary of all the 38 completed clinical trials related Roxadustat.
| Sr No. | NCT Number | Interventions | Study Title | Conditions | Sponsor: |
|---|---|---|---|---|---|
| 1 | NCT04076943 | Drug: Roxadustat | Evaluation of Efficacy and Safety of Roxadustat for the Treatment of Chemotherapy Induced Anemia Has Results |
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| 2 | NCT04454879 | Drug: Roxadustat | Different Doses of Roxadustat Treatment for Anemia in Peritoneal Dialysis Patients |
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| 3 | NCT04484857 | Drug: Roxadustat | Study of Roxadustat Conversion in Participants Receiving Stable ESA or as Initial Anemia Treatment in Hemodialysis Participants |
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|
| 4 | NCT04410198 | Drug: Roxadustat | Study of Roxadustat Conversion in Participants Receiving Stabe Erythropoiesis-Stimulating Agent (ESA) or as Initial Anemia Treatment in Chronic Dialysis Participants |
|
|
| 5 | NCT04655027 | Drug: Roxadustat Drug: rHuEPO |
A Study to Investigate the Effect of Roxadustat Versus Recombinant Human Erythropoietin (rHuEPO) on Oral Iron Absorption in Chinese Patients with Anemia of Chronic Kidney Disease (CKD) |
|
|
| 6 | NCT02273726 | Drug: Epoetin Alfa Drug: Roxadustat |
Study to Evaluate the Efficacy and Safety of Roxadustat in the Treatment of Anemia in Participants with ESRD on Stable Dialysis | •CKD Anemia in Stable Dialysis
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|
| 7 | NCT02965040 | Drug: Roxadustat | A Phase 1 Study of Roxadustat in Subjects with Different Degrees of Renal Function |
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| 8 | NCT04059913 | Drug: Roxadustat | Evaluate the Efficacy and Safety of Multiple Roxadustat Dosing Regimens for the Treatment of Anemia in Dialysis Participants with Chronic Kidney Disease | CKD Anemia in Dialysis
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|
| 9 | NCT03960489 | Drug: Roxadustat | A Study to Assess the Relative Bioavailability of Roxadustat Following a Single Dose of Pediatric Azo Dye-free Tablet Formulation and Pediatric Azo Dye-free Mini-tablet Formulation Compared to a Single Dose of Azo Dye-containing Tablet Formulation in Healthy Adult Subjects |
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|
| 10 | NCT01887600 | Drug: Roxadustat Drug: Placebo |
Roxadustat in the Treatment of Anemia in Chronic Kidney Disease Patients Not Requiring Dialysis |
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|
| 11 | NCT02052310 | Drug: Roxadustat Drug: Epoetin Alfa |
Safety and Efficacy Study of Roxadustat (FG-4592) for the Treatment of Anemia in End-Stage Renal Disease (ESRD) Newly Initiated Dialysis Participants |
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| 12 | NCT01630889 | Drug: Roxadustat | Open-Label Extension Study for the Long-Term Efficacy and Safety of Roxadustat in Participants with Dialysis and Non-Dialysis Chronic Kidney Disease |
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| 13 | NCT02161224 | Drug: FG-4592 | A Study to Investigate the Exposure and Safety and Tolerability of a Single Dose of FG-4592 in Subjects With Moderately Diminished Liver Function Compared to Those with Normal Liver Function |
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|
| 14 | NCT02021318 | Drug: Roxadustat Drug: Darbepoetin alfa |
Roxadustat in the Treatment of Anemia in Chronic Kidney Disease (CKD) Patients, Not on Dialysis, in Comparison to Darbepoetin Alfa |
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|
| 15 | NCT02161796 | Drug: FG-4592 Drug: Placebo |
A Study to Evaluate the Dose proportionality and Effects of FG-4592 in Healthy Young and Elderly Male and Female Subjects |
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| 16 | NCT02278341 | Drug: Roxadustat Drug: Epoetin alfa Drug: Darbepoetin alfa Drug: Iron |
Roxadustat in the Treatment of Anemia in End Stage Renal Disease (ESRD) Patients on Stable Dialysis |
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|
| 17 | NCT01750190 | Drug: Roxadustat Drug: Placebo |
A Study of Roxadustat for the Treatment of Anemia in Participants With Chronic Kidney Disease and Not Receiving Dialysis |
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| 18 | NCT01244763 | Drug: Roxadustat | Study of Roxadustat in Non- Dialysis Chronic Kidney Disease Participants with Anemia |
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| 19 | NCT02252731 | Drug: Warfarin Drug: FG-4592 |
A Study to Evaluate the Effects of Multiple Doses of FG-4592 on the Exposure, Safety and Tolerability and Effect of Warfarin in Healthy Subjects | Pharmacokinetics of FG-4592
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|
| 20 | NCT02174731 | Drug: Roxadustat Drug: Epoetin alfa |
Safety and Efficacy Study of Roxadustat to Treat Anemia in Patients with Chronic Kidney Disease, on Dialysis. |
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| 21 | NCT01147666 | Drug: Roxadustat Drug: Epoetin Alfa Other: Placebo |
Study of Roxadustat (FG-4592) in Participants with End-Stage Renal Disease Receiving Maintenance Hemodialysis |
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| 22 | NCT02174627 | Drug: Roxadustat Drug: Placebo |
Safety and Efficacy Study of Roxadustat to Treat Anemia in Patients with Chronic Kidney Disease (CKD), Not on Dialysis |
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| 23 | NCT00761657 | Drug: Roxadustat Drug: Placebo |
Phase 2 Study of Roxadustat in Participants with Anemia and Chronic Kidney Disease Not Requiring Dialysis |
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| 24 | NCT01414075 | Drug: Roxadustat Drug: Oral Iron Drug: IV Iron |
Study of Roxadustat (FG-4592) to Correct Anemia in Newly Initiated Dialysis Participants Not on Erythropoiesis-Stimulating Agent Treatment |
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|
| 25 | NCT01376063 | Drug: FG-4592 | Study to Investigate the Interaction Between FG-4592 and Rosiglitazone in Healthy Adult Subjects |
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| 26 | NCT01596855 | Drug: FG-4592 Drug: Epoetin Alfa |
Study of FG-4592 in Subjects with End-Stage Renal Disease Receiving Maintenance Hemodialysis in China |
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|
| 27 | NCT01599507 | Drug: FG-4592 Drug: Placebo |
Study of FG-4592 in Subjects with Chronic Kidney Disease in China |
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|
| 28 | NCT02652806 | Drug: FG-4592 Drug: Epoetin Alfa |
FG-4592 for Treatment of Anemia in Subjects with Chronic Kidney Disease |
|
|
| 29 | NCT02652819 | Drug: FG-4592 Drug: Placebo |
FG-4592 for Treatment of Anemia in Subjects with Chronic Kidney Disease Not on Dialysis |
|
|
| 30 | NCT02988973 | Drug: Roxadustat Drug: DA |
A Study of Intermittent Oral Dosing of ASP1517 in Non-Dialysis Chronic Kidney Disease Patients with Anemia |
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| 31 | NCT02780726 | Drug: Roxadustat | A Study of Intermittent Oral Dosing of ASP1517 in Peritoneal Dialysis Chronic Kidney Disease Patients With Anemia |
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| 32 | NCT02780141 | Drug: Roxadustat | A Study of Intermittent Oral Dosing of ASP1517 in Erythropoiesis Stimulating Agent (ESA)-Naive Hemodialysis Chronic Kidney Disease Patients with Anemia |
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| 33 | NCT02964936 | Drug: Roxadustat | A Study of Intermittent Oral Dosing of ASP1517 in ESA untreated Chronic Kidney Disease Patients with Anemia |
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| 34 | NCT02779764 | Drug: Roxadustat | A Long-Term Study of Intermittent Oral Dosing of ASP1517 in Hemodialysis Chronic Kidney Disease Patients with Anemia Converted From Erythropoiesis Stimulating Agent (ESA) Treatment |
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| 35 | NCT01083888 | Drug: Roxadustat | ASP1517 Pharmacokinetics Study in Anemia Patients on Hemodialysis |
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| 36 | NCT02952092 | Drug: Roxadustat Drug: Darbepoetin alfa |
A Study of Intermittent Oral Dosing of ASP1517 in Hemodialysis Chronic Kidney Disease Patients with Anemia |
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|
| 37 | NCT00978198 | Drug: ASP1517(Roxadustat) Drug: Placebo |
Safety, Tolerability, and Pharmacokinetic Study of ASP1517 in Healthy Non-elderly Male Volunteers |
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| 38 | NCT01888445 | Drug: Roxadustat Drug: darbepoetin alfa |
A Study to Investigate the Effect of ASP1517 After Intermittent Oral Dosing in Dialysis Chronic Kidney Disease Patients with Anemia Compared With Darbepoetin as a Reference Drug |
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