Table 2.
Adjusted Mean* (95% CI) | ||||
---|---|---|---|---|
Disease Outcomes | High Stress** (N=64) | Low/Moderate Stress (N=193) | P | Beta |
| ||||
SLE Disease Activity: | ||||
Physician-assessed disease activity1 | 2.5 (1.8, 3.3) | 3.0 (2.6, 3.5) | 0.251 | −0.51 |
Self-reported disease activity2 | 14.0 (12.3, 15.6) | 7.4 (6.5, 8.3) | <0.001 | 6.56 |
Symptoms: | ||||
Pain Interference3 | 58.4 (56.1, 60.6) | 50.2 (48.9, 51.5) | <0.001 | 8.13 |
Fatigue4 | 60.2 (57.6, 62.9) | 49.3 (47.8, 50.7) | <0.001 | 10.96 |
Adjusted means calculated from multivariable regression analysis adjusted for age, sex, race and ethnicity, educational attainment, smoking, and disease duration. The N for the multivariable regression was 257 (vs. 260 eligible participants) as 3 participants had missing data for smoking status.
Participants with scores in the top quartile for the 4-item Perceived Stress Scale.
Assessed by Systemic Lupus Disease Activity Index (SLEDAI), score range 0 – 105.
Assessed by Systemic Lupus Activity Questionnaire (SLAQ), score range 0 – 44.
Assessed by Patient-Reported Outcome Measurement Information System (PROMIS) 4-item Pain Interference scale, score range 41.6 – 75.6.
Assessed by PROMIS 4-item Fatigue scale, score range 33.7 – 75.89.