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. 2023 Jun 2;9(6):e16919. doi: 10.1016/j.heliyon.2023.e16919

Fig. 4.

Fig. 4

Main mechanisms by which p53 deals with DNA damage. p53, a tumor suppressor protein, employs multiple mechanisms to address DNA damage. It halts the cell cycle, activates DNA repair, promotes cellular senescence, and induces apoptosis. These processes collectively maintain genomic stability, prevent the propagation of mutations, and inhibit the development and progression of cancer.