Figure 1.

Experimental protocol for the development of allergic rhinitis and treatment with SJMHE1. BALB/c mice were sensitized with OVA and aluminum hydroxide in PBS on days 0, 7 and 14 by intraperitoneal injection (i.p.). Subsequently, the sensitized mice were challenged intranasally with OVA daily from days 21 to 27 and 29 to 35. PBS, emulsified OVA^323-339 or SJMHE1 with incomplete Freund’s adjuvant were subcutaneously (inner thigh) injected into mice on days 0, 14 and 28. The mice were sacrificed on day 36 and the samples were collected.